Croma Saypha® Hyaluronic Acid Fillers

Saypha® is the flagship hyaluronic acid dermal filler from Croma-Pharma, Austria's leading pharmaceutical innovator with nearly 50 years of expertise. As the first HA filler to achieve full EU MDR certification, Saypha® sets the gold standard for safety, efficacy, and regulatory compliance in aesthetic medicine.

Powered by MACRO Core Technology, Saypha® delivers optimal tissue integration and natural-looking results. Its ultra-pure formulation contains less than 2 ppm BDDE residuals and boasts an exceptional 0.005% complaint rate, reflecting unparalleled quality control and patient satisfaction.

Key Features

  • Certified Safety: Fully MDR certified with ultra-pure HA (<2 ppm BDDE) and a 0.005% complaint rate.

  • ComfortFlow Syringe: Premium glass syringe designed for smooth extrusion and precise control.

  • Long-Lasting Results: Clinical data shows improvement lasting up to 9–12 months.

  • Austrian Manufacturing: Produced in Vienna with nearly 50 years of pharmaceutical expertise.

Technical Specifications

Product Indication HA Conc. Injection Depth
Saypha® FILLER Lidocaine Moderate nasolabial folds & facial wrinkles. 23 mg/mL Mid to Deep Dermis
Saypha® VOLUME Lidocaine Deep nasolabial folds & facial volumizing. 23 mg/mL Deep Dermis
Saypha® VOLUME PLUS Lidocaine Severe midface volume deficit & contouring. 25 mg/mL Subcutaneous / Supraperiosteal
Needle Concept

Mesbio Needle

Premium medical-grade needles designed for precision aesthetic treatments. Engineered in France with ultra-thin walls for optimal flow and minimal trauma.
ISO 13485
Medical Device Class IIa

Face

Precision facial treatments

Hair

Hair restoration therapy

Body

Body contouring applications

Made in France

Medical-grade quality

Needle Gauge Sizes

27G
Ø 0.40
30G
Ø 0.30
31G
Ø 0.25
32G
Ø 0.23
33G
Ø 0.20
34G
Ø 0.18

Technical Specifications

Gauge (Color) Diameter Available Lengths
27G Ø 0.40 4mm, 6mm, 12mm
30G Ø 0.30 4mm, 6mm, 12mm
31G Ø 0.25 4mm, 8mm, 12mm
32G Ø 0.23 4mm, 6mm, 12mm
33G Ø 0.20 4mm, 8mm, 12mm
34G Ø 0.18 4mm, 8mm, 12mm

Packaging Details

  • Box of 100 needles
  • Sterile blister packaging
  • Single-use, disposable
Needle Concept

Magic Needle Cannula

Premium medical-grade cannulas designed for precision aesthetic procedures with minimal patient discomfort and optimal results.

Face & Body Applications

Natural Homogeneous Results

Less Bruising & Pain

No Social Eviction

Single-Point Injection Coverage

Medical-Grade Quality

Made in France

Available Gauge Sizes

14G
2.1mm
16G
1.6mm
18G
1.2mm
20G
0.9mm
22G
0.7mm
23G
0.6mm
25G
0.5mm
27G
0.4mm
30G
0.3mm

Technical Specifications

Gauge Color Cannula Size & Lengths Pilot Needle Included
14G 14G - 27mm, 40mm, 50mm, 70mm, 90mm 14G 12
16G 16G - 27mm, 40mm, 50mm, 70mm, 90mm 16G 12
18G 18G - 27mm, 40mm, 50mm, 70mm, 90mm 18G 12
20G 20G - 27mm, 40mm, 50mm, 70mm, 90mm 20G 12
22G 22G - 27mm, 40mm, 50mm, 70mm, 90mm 22G 12
23G 23G - 27mm, 40mm, 50mm, 70mm, 90mm 23G 12
25G 25G - 27mm, 40mm, 50mm, 70mm, 90mm 25G 12
27G 27G - 27mm, 40mm, 50mm, 70mm, 90mm 27G 12
Flexible Blunt-Tip Design
Innovative Surface Treatment
Luer-Lock Compatibility
ISO 13485 Certified
Medical Device Class IIa

Packing Details

Box of 25 kits
Sterile blister with cannula plus pilot needle

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